| Date | Home | Away | Result |
|---|---|---|---|
| 24/10/25 20:00 | Leeds United | West Ham United | 2-1 |
| 25/10/25 15:00 | Chelsea FC | AFC Sunderland | 1-2 |
| 25/10/25 15:00 | Newcastle United | Fulham FC | 2-1 |
| 25/10/25 17:30 | Manchester United | Brighton and Hove Albion | 4-2 |
| 25/10/25 20:00 | Brentford FC | Liverpool FC | 3-2 |
| 26/10/25 14:00 | AFC Bournemouth | Nottingham Forest | 2-0 |
| 26/10/25 14:00 | Wolverhampton Wanderers | Burnley FC | 2-3 |
| 26/10/25 14:00 | Aston Villa | Manchester City | 1-0 |
| 26/10/25 14:00 | Arsenal FC | Crystal Palace | 1-0 |
| 26/10/25 16:30 | Everton FC | Tottenham Hotspur | 0-3 |